Scientists Can Now Block Heroin, Morphine Addiction

In a major breakthrough, an international team of scientists has proven that addiction to morphine and heroin can be blocked, while at the same time increasing pain relief.

Photp: Jens Langner at http://commons.wikimedia.org/wiki/File:PET-image.jpg

Laboratory studies have shown that the drug (+)-naloxone (pronounced: PLUS nal-OX-own) will selectively block the immune-addiction response.The team from the University of Adelaide and University of Colorado has discovered the key mechanism in the body's immune system that amplifies addiction to opioid drugs.

The results -- which could eventually lead to new co-formulated drugs that assist patients with severe pain, as well as helping heroin users to kick the habit -- will be published August 16 in the Journal of Neuroscience.

"Our studies have shown conclusively that we can block addiction via the immune system of the brain, without targeting the brain's wiring," says the lead author of the study, Dr Mark Hutchinson, ARC Research Fellow in the University of Adelaide's School of Medical Sciences.

"Both the central nervous system and the immune system play important roles in creating addiction, but our studies have shown we only need to block the immune response in the brain to prevent cravings for opioid drugs."

The team has focused its research efforts on the immune receptor known as Toll-Like receptor 4 (TLR4).

"Opioid drugs such as morphine and heroin bind to TLR4 in a similar way to the normal immune response to bacteria. The problem is that TLR4 then acts as an amplifier for addiction," Dr Hutchinson says.

"The drug (+)-naloxone automatically shuts down the addiction. It shuts down the need to take opioids, it cuts out behaviours associated with addiction, and the neurochemistry in the brain changes -- dopamine, which is the chemical important for providing that sense of 'reward' from the drug, is no longer produced."

Senior author Professor Linda Watkins, from the Center for Neuroscience at the University of Colorado Boulder, says: "This work fundamentally changes what we understand about opioids, reward and addiction. We've suspected for some years that TLR4 may be the key to blocking opioid addiction, but now we have the proof.

"The drug that we've used to block addiction, (+)-naloxone, is a non-opioid mirror image drug that was created by Dr Kenner Rice in the 1970s. We believe this will prove extremely useful as a co-formulated drug with morphine, so that patients who require relief for severe pain will not become addicted but still receive pain relief. This has the potential to lead to major advances in patient and palliative care," Professor Watkins says.

The researchers say clinical trials may be possible within the next 18 months.

This study has been funded by the National Institute on Drug Abuse (NIDA) in the United States and the Australian Research Council (ARC).

Source: University of Adelaide (2012, August 14). Scientists can now block heroin, morphine addiction. ScienceDaily. Retrieved April 24, 2013, from http://www.sciencedaily.com­/releases/2012/08/120814213246.htm

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The Power of Suggestion: What We Expect Influences Our Behavior, for Better or Worse

A lucky rabbit foot. A glass of wine. A pill. What do these things all have in common? Their effects -- whether we do well on a test, whether we mingle at the cocktail party, whether we feel better -- all depend on the power of suggestion.

In a new article, psychological scientists Maryanne Garry and Robert Michael of Victoria University of Wellington, along with Irving Kirsch of Harvard Medical School and Plymouth University, delve into the phenomenon of suggestion, exploring the intriguing relationship between suggestion, cognition, and behavior. The article is published in the June issue of Current Directions in Psychological Science, a journal of the Association for Psychological Science.

Over their research careers, Garry and Kirsch have both studied the effects of suggestion on cognition and behavior. Kirsch focused mostly on suggestion in clinical psychology, while Garry, whose work is supported by the Marsden Fund of New Zealand, was interested in the effects of suggestion on human memory. When the two got to talking, "we realized that the effects of suggestion are wider and often more surprising than many people might otherwise think," says Garry.

Across many studies, research has shown that deliberate suggestion can influence how people perform on learning and memory tasks, which products they prefer, and how they respond to supplements and medicines, which accounts for the well-known placebo effect.

But what can explain the powerful and pervasive effect that suggestion has in our lives? The answer lies in our 'response expectancies,' or the ways in which we anticipate our responses in various situations. These expectancies set us up for automatic responses that actively influence how we get to the outcome we expect. Once we anticipate a specific outcome will occur, our subsequent thoughts and behaviors will actually help to bring that outcome to fruition.

So, if a normally shy person expects that a glass of wine or two will help him loosen up at a cocktail party, he will probably feel less inhibited, approach more people, and get involved in more conversations over the course of the party. Even though he may give credit to the wine, it is clear that his expectations of how the wine would make him feel played a major role.

But it's not just deliberate suggestion that influences our thoughts and behaviors -- suggestions that are not deliberate can have the very same effects. As the authors point out, "simply observing people or otherwise making them feel special can be suggestive," a phenomenon termed the Hawthorne effect. As a result, people might work harder, or stick to a task for longer. And this case is more worrying, says Garry, "because although we might then give credit to some new drug or treatment, we don't realize that we are the ones who are actually wielding the influence."

It is for precisely this reason that the issue of unintentional suggestion has important implications for academic researchers. "In the scientific community, we need to be aware of -- and control for -- the suggestions we communicate to subjects," says Garry. The authors note that some recent failures to replicate previous research findings may ultimately be explained by such unintentional suggestion. "Recent research suggests that some of psychological science's most intriguing findings may be driven, at least in part, by suggestion and expectancies," Garry observes. "For example, a scientist who knows what the hypothesis of an experiment is might unwittingly lead subjects to produce the hypothesized effect -- for reasons that have nothing to do with the experiment itself."

And the unintended effects of suggestion aren't just restricted to the laboratory -- they cut across many real world domains, including the fields of medicine, education, and criminal justice. For example, converging evidence on eyewitness identification procedures demonstrates that the rate of false identifications is significantly higher when lineups are conducted by people who know who the suspect is than when the lineups are conducted by people who don't.

While research has provided clear evidence for the phenomenon of suggestion, there is still much more to learn about the underlying relationship between suggestion, cognition, and behavior. As the authors point out, researchers still don't know where the boundaries and limitations of these effects lie. "And, if a 'real' treatment and a 'suggestion' lead to a similar outcome, what differentiates between the two?" says Garry. Understanding these issues has important real world implications. "If we can harness the power of suggestion, we can improve people's lives."

Source: Association for Psychological Science [June 06, 2012]

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Statistical Model Attempting to Estimate Level of Alcohol Consumption That Is 'Optimal' for Health

Cutting the amount we drink to just over half a unit a day could save 4,600 lives a year in England, according to a modelling study by Oxford University researchers published in the journal BMJ Open.

Half a unit of alcohol is as little as a quarter of a glass of wine, or a quarter of a pint [Credit: © G.G. Lattek / Fotolia]

Scientists have carried out a complex analysis in an attempt to determine the "optimal" level of alcohol consumption that is associated with the lowest rates of chronic disease in the UK. They conclude that the intake of about one-half of a typical drink per day would result in the healthiest outcomes, and the authors conclude that the recommended alcohol intake for the UK should be reduced from the current advised level of drinking.

Half a unit of alcohol is as little as a quarter of a glass of wine, or a quarter of a pint. That's much lower than current government recommendations of between 3 to 4 units a day for men and 2-3 units for women.

The researchers set out to find the optimum daily amount of alcohol that would see fewest deaths across England from a whole range of diseases connected to drink. Previous studies have often looked at the separate effects of alcohol on heart disease, liver disease or cancers in isolation.

'Although there is good evidence that moderate alcohol consumption protects against heart disease, when all of the chronic disease risks are balanced against each other, the optimal consumption level is much lower than many people believe,' says lead author Dr Melanie Nichols of the BHF Health Promotion Research Group in the Department of Public Health at Oxford University.

The team used a mathematical model to assess what impact changing average alcohol consumption would have on deaths from 11 conditions known to be at least partially linked to drink.

These included coronary heart disease, stroke, high blood pressure, diabetes, cirrhosis of the liver, epilepsy, and five cancers. Over 170,000 people in England died from these 11 conditions in 2006, and ill health linked to alcohol is estimated to cost the NHS in England £3.3 billion every year.

The researchers used information from the 2006 General Household Survey on levels of alcohol consumption among adults in England. They combined this with the disease risks for differing levels of alcohol consumption as established in large analyses of published research.

They found that just over half a unit of alcohol a day was the optimal level of consumption among current drinkers.

They calculate this level of drinking would prevent around 4,579 premature deaths, or around 3% of all deaths from the 11 conditions.

The number of deaths from heart disease would increase by 843, but this would be more than offset by around 2,600 fewer cancer deaths and almost 3,000 fewer liver cirrhosis deaths.

'Moderating your alcohol consumption overall, and avoiding heavy-drinking episodes, is one of several things, alongside a healthy diet and regular physical activity, that you can do to reduce your risk of dying early of chronic diseases,' says Dr Nichols.

She adds: 'We are not telling people what to do, we are just giving them the best balanced information about the different health effects of alcohol consumption, so that they can make an informed decision about how much to drink.

'People who justify their drinking with the idea that it is good for heart disease should also consider how alcohol is increasing their risk of other chronic diseases. A couple of pints or a couple of glasses of wine per day is not a healthy option.'

Although this study in BMJ Open did not look at patterns of drinking, Dr Nichols says: 'Regardless of your average intake, if you want to have the best possible health, it is also very important to avoid episodes of heavy drinking ("binge drinking") as there is very clear evidence that this will increase your risks of many diseases, as well as your risk of injuries.'

Source: University of Oxford [June 06, 2012]

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To Quit Smoking, Try Eating More Veggies and Fruits

If you're trying to quit smoking, eating more fruits and vegetables may help you quit and stay tobacco-free for longer, according to a new study published online by University at Buffalo public health researchers.

If you're trying to quit smoking, eating more fruits and vegetables may help you quit and stay tobacco-free for longer [Credit: © taviphoto / Fotolia]

The paper, in the journal Nicotine and Tobacco Research, is the first longitudinal study on the relationship between fruit and vegetable consumption and smoking cessation.

The authors, from UB's School of Public Health and Health Professions, surveyed 1,000 smokers aged 25 and older from around the country, using random-digit dialing telephone interviews. They followed up with the respondents fourteen months later, asking them if they had abstained from tobacco use during the previous month.

"Other studies have taken a snapshot approach, asking smokers and nonsmokers about their diets," says Gary A. Giovino, PhD, chair of the Department of Community Health and Health Behavior at UB. "We knew from our previous work that people who were abstinent from cigarettes for less than six months consumed more fruits and vegetables than those who still smoked. What we didn't know was whether recent quitters increased their fruit and vegetable consumption or if smokers who ate more fruits and vegetables were more likely to quit."

The UB study found that smokers who consumed the most fruit and vegetables were three times more likely to be tobacco-free for at least 30 days at follow-up 14 months later than those consuming the lowest amount of fruits and vegetables. These findings persisted even when adjustments were made to take into account age, gender, race/ethnicity, education, household income and health orientation.

They also found that smokers with higher fruit and vegetable consumption smoked fewer cigarettes per day, waited longer to smoke their first cigarette of the day and scored lower on a common test of nicotine dependence.

"We may have identified a new tool that can help people quit smoking," says Jeffrey P. Haibach, MPH, first author on the paper and graduate research assistant in the UB Department of Community Health and Health Behavior. "Granted, this is just an observational study, but improving one's diet may facilitate quitting."

Several explanations are possible, such as less nicotine dependence for people who consume a lot of fruits and vegetables or the fact that higher fiber consumption from fruits and vegetables make people feel fuller.

"It is also possible that fruits and vegetables give people more of a feeling of satiety or fullness so that they feel less of a need to smoke, since smokers sometimes confuse hunger with an urge to smoke," explains Haibach.

And unlike some foods which are known to enhance the taste of tobacco, such as meats, caffeinated beverages and alcohol, fruits and vegetables do not enhance the taste of tobacco.

"Foods like fruit and vegetables may actually worsen the taste of cigarettes," says Haibach.

While smoking rates in the U.S. continue to decline, Giovino notes, the rate of that decline has slowed during the past decade or so. "Nineteen percent of Americans still smoke cigarettes, but most of them want to quit," he says.

Haibach adds: "It's possible that an improved diet could be an important item to add to the list of measures to help smokers quit. We certainly need to continue efforts to encourage people to quit and help them succeed, including proven approaches like quitlines, policies such as tobacco tax increases and smoke-free laws, and effective media campaigns."

The UB researchers caution that more research is needed to determine if these findings replicate and if they do, to identify the mechanisms that explain how fruit and vegetable consumption may help smokers quit. They also see a need for research on other dietary components and smoking cessation.

Gregory G. Homish, PhD, assistant professor in the UB Department of Community Health and Health Behavior, also is a co-author.

Funding was provided by the Robert Wood Johnson Foundation and LegacyA®.

Source: University at Buffalo [June 06, 2012]

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Female Choice Key to Evolutionary Shift to Modern Family

It is a question that has puzzled evolutionary biologists for years: Why did we stop being promiscuous and decide to settle down to start families?

Sergey Gavrilets, professor of ecology and evolutionary biology at the University of Tennessee, Knoxville, may have found the answer, and it lies in the power of female choice. The study reveals how females chose their mates played a critical role in human evolution by leading to monogamous relationships, which laid the foundation for the institution of the modern family.

Using mathematical modeling, the associate director for scientific activities at the National Institute for Mathematical and Biological Synthesis (NIMBioS) at UT has discovered that the transformation may have occurred when early-hominid females started choosing males who were good providers.

Gavrilets' findings are published in the Proceedings of the National Academy of Sciences.

The "sexual revolution" entailed males first competing with other males for dominance, as a way to get matings. However, low-ranked males—and eventually all males except those with the highest societal stature—began supplying females with provisions in what is called "food-for-mating" to get a leg up on the competition. Females showed preference for the "provisioning" males, leading males' energy to be spent on providing for females and females becoming increasingly faithful. This spurred self-domestication and the modern family as we know it today.

"This change has confounded scientists for a long time because many species would be much better off evolutionarily if the effort spent on males competing for mates was redirected towards increasing female fertility or survivorship of their offspring," said Gavrilets.

The study demonstrates mathematically that the most commonly proposed theories for the transition to human pair bonding—or coupling—are not biologically feasible.

However, the study advances a new model showing that the transition to pair-bonding can occur when female choice and faithfulness, among other factors, are included. The result is an increased emphasis on males provisioning females over male competition for mating.

"The study reveals that female choice played a crucial role in human evolution," said Gavrilets.

According to Gavrilets, the transition to coupling has opened the path to intensified male parental investment, which was a breakthrough adaptation with multiple anatomical, behavioral and physiological consequences for early hominids and for all of their descendants. It shifted the dynamic away from males competing with each other for sex to males competing with each other to see who is a better provider to get better mates.

"Pair bonding laid the foundation for a later emergence of the institution of the modern family," said Gavrilets.

Source: University of Tennessee [May 30, 2012]

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How Exercise Affects the Brain

Exercise clears the mind. It gets the blood pumping and more oxygen is delivered to the brain. This is familiar territory, but Dartmouth's David Bucci thinks there is much more going on.

Exercise clears the mind. It gets the blood pumping and more oxygen is delivered to the brain. This is familiar territory, but Dartmouth's David Bucci thinks there is much more going on [Credit: Web]

"In the last several years there have been data suggesting that neurobiological changes are happening -- [there are] very brain-specific mechanisms at work here," says Bucci, an associate professor in the Department of Psychological and Brain Sciences.

From his studies, Bucci and his collaborators have revealed important new findings:

• The effects of exercise are different on memory as well as on the brain, depending on whether the exerciser is an adolescent or an adult.

• A gene has been identified which seems to mediate the degree to which exercise has a beneficial effect. This has implications for the potential use of exercise as an intervention for mental illness.

Bucci began his pursuit of the link between exercise and memory with attention deficit hyperactivity disorder (ADHD), one of the most common childhood psychological disorders. Bucci is concerned that the treatment of choice seems to be medication.

"The notion of pumping children full of psycho-stimulants at an early age is troublesome," Bucci cautions. "We frankly don't know the long-term effects of administering drugs at an early age -- drugs that affect the brain -- so looking for alternative therapies is clearly important."

Anecdotal evidence from colleagues at the University of Vermont started Bucci down the track of ADHD. Based on observations of ADHD children in Vermont summer camps, athletes or team sports players were found to respond better to behavioral interventions than more sedentary children. While systematic empirical data is lacking, this association of exercise with a reduction of characteristic ADHD behaviors was persuasive enough for Bucci.

Coupled with his interest in learning and memory and their underlying brain functions, Bucci and teams of graduate and undergraduate students embarked upon a project of scientific inquiry, investigating the potential connection between exercise and brain function. They published papers documenting their results, with the most recent now available in the online version of the journal Neuroscience.

Bucci is quick to point out that "the teams of both graduate and undergraduates are responsible for all this work, certainly not just me." Michael Hopkins, a graduate student at the time, is first author on the papers.

Early on, laboratory rats that exhibit ADHD-like behavior demonstrated that exercise was able to reduce the extent of these behaviors. The researchers also found that exercise was more beneficial for female rats than males, similar to how it differentially affects male and female children with ADHD.

Moving forward, they investigated a mechanism through which exercise seems to improve learning and memory. This is "brain derived neurotrophic factor" (BDNF) and it is involved in growth of the developing brain. The degree of BDNF expression in exercising rats correlated positively with improved memory, and exercising as an adolescent had longer lasting effects compared to the same duration of exercise, but done as an adult.

"The implication is that exercising during development, as your brain is growing, is changing the brain in concert with normal developmental changes, resulting in your having more permanent wiring of the brain in support of things like learning and memory," says Bucci. "It seems important to [exercise] early in life."

Bucci's latest paper was a move to take the studies of exercise and memory in rats and apply them to humans. The subjects in this new study were Dartmouth undergraduates and individuals recruited from the Hanover community.

Bucci says that, "the really interesting finding was that, depending on the person's genotype for that trophic factor [BDNF], they either did or did not reap the benefits of exercise on learning and memory. This could mean that you may be able to predict which ADHD child, if we genotype them and look at their DNA, would respond to exercise as a treatment and which ones wouldn't."

Bucci concludes that the notion that exercise is good for health including mental health is not a huge surprise. "The interesting question in terms of mental health and cognitive function is how exercise affects mental function and the brain." This is the question Bucci, his colleagues, and students continue to pursue.

Author: Joseph Blumberg | Source: Dartmouth College [May 18, 2013]

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A walk in the park gives mental boost to people with depression

A walk in the park may have psychological benefits for people suffering from depression. In one of the first studies to examine the effect of nature walks on cognition and mood in people with major depression, researchers in Canada and the U.S. have found promising evidence that a walk in the park may provide some cognitive benefits.

The study was led by Marc Berman, a post-doctoral fellow at Baycrest's Rotman Research Institute in Toronto, with partners from the University of Michigan and Stanford University. It is published online this week, ahead of print publication, in the Journal of Affective Disorders.

"Our study showed that participants with clinical depression demonstrated improved memory performance after a walk in nature, compared to a walk in a busy urban environment," said Dr. Berman, who cautioned that such walks are not a replacement for existing and well-validated treatments for clinical depression, such as psychotherapy and drug treatment.

"Walking in nature may act to supplement or enhance existing treatments for clinical depression, but more research is needed to understand just how effective nature walks can be to help improve psychological functioning," he said.

Dr. Berman's research is part of a cognitive science field known as Attention Restoration Theory (ART) which proposes that people concentrate better after spending time in nature or looking at scenes of nature. The reason, according to ART, is that people interacting with peaceful nature settings aren't bombarded with external distractions that relentlessly tax their working memory and attention systems. In nature settings, the brain can relax and enter a state of contemplativeness that helps to restore or refresh those cognitive capacities.

In a research paper he published in 2008 in Psychological Science, Dr. Berman showed that adults who were not diagnosed with any illness received a mental boost after an hour-long walk in a woodland park – improving their performance on memory and attention tests by 20 percent – compared to an hour-long stroll in a noisy urban environment. The findings were reported by The Wall Street Journal, The Boston Globe, The New York Times, and in the Pulitzer Prize finalist book by Nicholas Carr, The Shallows: What the internet is doing to our brains.

In this latest study, Dr. Berman and his research team explored whether a nature walk would provide similar cognitive benefits, and also improve mood for people with clinical depression. Given that individuals with depression are characterized by high levels of rumination and negative thinking, the researchers were skeptical at the outset of the study that a solitary walk in the park would provide any benefit at all and may end up worsening memory and exacerbating depressed mood.

For the study, 20 individuals were recruited from the University of Michigan and surrounding Ann Arbor area; all had a diagnosis of clinical depression. The 12 females and eight males (average age 26) participated in a two-part experiment that involved walking in a quiet nature setting and in a noisy urban setting.

Prior to the walks, participants completed baseline testing to determine their cognitive and mood status. Before beginning a walk, the participants were asked to think about an unresolved, painful autobiographical experience. They were then randomly assigned to go for an hour-long walk in the Ann Arbor Arboretum (woodland park) or traffic heavy portions of downtown Ann Arbor. They followed a prescribed route and wore a GPS watch to ensure compliance.

After completing their walk, they completed a series of mental tests to measure their attention and short-term/working memory and were re-asssessed for mood. A week later the participants repeated the entire procedure, walking in the location that was not visited in the first session.

Participants exhibited a 16 percent increase in attention and working memory after the nature walk relative to the urban walk. Interestingly, interacting with nature did not alleviate depressive mood to any noticeable degree over urban walks, as negative mood decreased and positive mood increased after both walks to a significant and equal extent. Dr. Berman says this suggests that separate brain mechanisms may underlie the cognitive and mood changes of interacting with nature. 

Source: Baycrest Centre for Geriatric Care [May 14, 2012]

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Genes and Vascular Risk Modify Effects of Aging On Brain and Cognition

Efforts to understand how the aging process affects the brain and cognition have expanded beyond simply comparing younger and older adults.

"Everybody ages differently. By looking at genetic variations and individual differences in markers of vascular health, we begin to understand that preventable factors may affect our chances for successful aging," said Wayne State University psychology doctoral student Andrew Bender, lead author of a study supported by the National Institute on Aging of the National Institutes of Health and now in press in the journal Neuropsychologia.

The report, "Age-related Differences in Memory and Executive Functions in Healthy APOE ε4 Carriers: The Contribution of Individual Differences in Prefrontal Volumes and Systolic Blood Pressure," focuses on carriers of the ε4 variant of the apolipoprotein (APOE) gene, present in roughly 25 percent of the population. Compared to those who possess other forms of the APOE gene, carriers of the ε4 allele are at significantly greater risk for Alzheimer's, dementia and cardiovascular disease.

Many studies also have shown that nondemented carriers of the APOE ε4 variant have smaller brain volumes and perform less well on cognitive tests than carriers of other gene variants. Those findings, however, are not consistent, and a possible explanation may come from examining interactions between the risky genes and other factors, such as markers of cardiovascular health. Prior research in typical samples of older adults has shown that indeed other vascular risk factors -- such as elevated cholesterol, hypertension or diabetes -- can exacerbate the impact of the APOE ε4 variant on brain and cognition, but it is unclear if such synergy of risks is present in healthy adults.

Thus, Wayne State researchers evaluated a group of volunteers from 19 to 77 years of age who self-reported as exceptionally healthy on a questionnaire that screened for a number of conditions, representing a "best case scenario" of healthy aging. The research project, led by Naftali Raz, Ph.D., professor of psychology and director of the Lifespan Cognitive Neuroscience Research Program at WSU's Institute of Gerontology, tested different cognitive abilities known for their sensitivity to aging and the effects of the APOE ε4 variant. Those abilities include speed of information processing, working memory (holding and manipulating information in one's mind) and episodic memory (memory for events).

Researchers also measured participants' blood pressure, performed genetic testing to determine which APOE variant participants carried, and measured the volumes of several critical brain regions using a high-resolution structural magnetic resonance imaging brain scan. Bender and Raz showed that for older APOE ε4 carriers, even minor increases in systolic blood pressure (the higher of the two numbers that are reported in blood pressure measures) were linked with smaller volumes of the prefrontal cortex and prefrontal white matter, slower speed of information processing, reduced working memory capacity and worse verbal memory. Notably, they said, that pattern was not evident in those who lacked the ε4 gene variant.

The study concludes that the APOE ε4 gene may make its carriers sensitive to negative effects of relatively subtle elevations in systolic blood pressure, and that the interplay between two risk factors, genetic and physiological, is detrimental to the key brain structures and associated cognitive functions.

"Although genes play a significant role in shaping the effects of age and vascular risk on the brain and cognition, the impact of single genetic variants is relatively small, and there are quite a few of them. Thus, one's aging should not be seen through the lens of one's genetic profile," cautioned the study's authors. They continued, "The negative impact of many genetic variations needs help from other risk factors, and while there isn't much one can do about genes, a lot can be done about vascular risk factors such as blood pressure or cholesterol."

"Everybody should try to keep those in check, although people with certain genetic variants more so than others." Raz said. "Practically speaking, even with the best deck of genetic cards dealt to you, it still makes sense to reduce risk through whatever works: exercise, diet or, if those fail, medication."

Because the study is part of a longitudinal project, he and Bender said the immediate future task now is to determine how the interaction between risky genes and vascular risk factors affect the trajectory of age-related changes -- not differences, as in this cross-sectional study -- in brain and cognition.

Source: Wayne State University - Office of the Vice President for Research [May 09, 2012]

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Psychologists reveal how emotion can shut down high-level mental processes without our knowledge

Psychologists at Bangor University believe that they have glimpsed for the first time, a process that takes place deep within our unconscious brain, where primal reactions interact with higher mental processes. Writing in the Journal of Neuroscience, they identify a reaction to negative language inputs which shuts down unconscious processing.

For the last quarter of a century, psychologists have been aware of, and fascinated by the fact that our brain can process high-level information such as meaning outside consciousness. What the psychologists at Bangor University have discovered is the reverse- that our brain can unconsciously 'decide' to withhold information by preventing access to certain forms of knowledge.

The psychologists extrapolate this from their most recent findings working with bilingual people. Building on their previous discovery that bilinguals subconsciously access their first language when reading in their second language; the psychologists at the School of Psychology and Centre for Research on Bilingualism have now made the surprising discovery that our brain shuts down that same unconscious access to the native language when faced with a negative word such as war, discomfort, inconvenience, and unfortunate.

They believe that this provides the first proven insight to a hither-to unproven process in which our unconscious mind blocks information from our conscious mind or higher mental processes.

This finding breaks new ground in our understanding of the interaction between emotion and thought in the brain. Previous work on emotion and cognition has already shown that emotion affects basic brain functions such as attention, memory, vision and motor control, but never at such a high processing level as language and understanding.

Key to this is the understanding that people have a greater reaction to emotional words and phrases in their first language- which is why people speak to their infants and children in their first language despite living in a country which speaks another language and despite fluency in the second. It has been recognised for some time that anger, swearing or discussing intimate feelings has more power in a speaker's native language. In other words, emotional information lacks the same power in a second language as in a native language.

Dr Yan Jing Wu of the University's School of Psychology said: "We devised this experiment to unravel the unconscious interactions between the processing of emotional content and access to the native language system. We think we've identified, for the first time, the mechanism by which emotion controls fundamental thought processes outside consciousness.

"Perhaps this is a process that resembles the mental repression mechanism that people have theorised about but never previously located."

So why would the brain block access to the native language at an unconscious level?

Professor Guillaume Thierry explains: "We think this is a protective mechanism. We know that in trauma for example, people behave very differently. Surface conscious processes are modulated by a deeper emotional system in the brain. Perhaps this brain mechanism spontaneously minimises negative impact of disturbing emotional content on our thinking, to prevent causing anxiety or mental discomfort."

He continues: "We were extremely surprised by our finding. We were expecting to find modulation between the different words- and perhaps a heightened reaction to the emotional word -- but what we found was the exact opposite to what we expected- a cancellation of the response to the negative words."

The psychologists made this discovery by asking English-speaking Chinese people whether word pairs were related in meaning. Some of the word pairs were related in their Chinese translations. Although not consciously acknowledging a relation, measurements of electrical activity in the brain revealed that the bilingual participants were unconsciously translating the words. However, uncannily, this activity was not observed when the English words had a negative meaning.

Source: Bangor University [May 08, 2012]

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'Losing yourself' in a fictional character can affect your real life

When you "lose yourself" inside the world of a fictional character while reading a story, you may actually end up changing your own behavior and thoughts to match that of the character, a new study suggests.

Researchers at Ohio State University examined what happened to people who, while reading a fictional story, found themselves feeling the emotions, thoughts, beliefs and internal responses of one of the characters as if they were their own - a phenomenon the researchers call "experience-taking."

They found that, in the right situations, experience-taking may lead to real changes, if only temporary, in the lives of readers.

In one experiment, for example, the researchers found that people who strongly identified with a fictional character who overcame obstacles to vote were significantly more likely to vote in a real election several days later.

"Experience-taking can be a powerful way to change our behavior and thoughts in meaningful and beneficial ways," said Lisa Libby, co-author of the study and assistant professor of psychology at Ohio State University.

There are many ways experience-taking can affect readers.

In another experiment, people who went through this experience-taking process while reading about a character who was revealed to be of a different race or sexual orientation showed more favorable attitudes toward the other group and were less likely to stereotype.

"Experience-taking changes us by allowing us to merge our own lives with those of the characters we read about, which can lead to good outcomes," said Geoff Kaufman, who led the study as a graduate student at Ohio State. He is now a postdoctoral researcher at the Tiltfactor Laboratory at Dartmouth College.

Their findings appear online in the Journal of Personality and Social Psychology and will be published in a future print edition.

Experience-taking doesn't happen all the time. It only occurs when people are able, in a sense, to forget about themselves and their own self-concept and self-identity while reading, Kaufman said. In one experiment, for example, the researchers found that most college students were unable to undergo experience-taking if they were reading in a cubicle with a mirror.

"The more you're reminded of your own personal identity, the less likely you'll be able to take on a character's identity," Kaufman said.

"You have to be able to take yourself out of the picture, and really lose yourself in the book in order to have this authentic experience of taking on a character's identity."

In the voting study, 82 undergraduates who were registered and eligible to vote were assigned to read one of four versions of a short story about a student enduring several obstacles on the morning of Election Day (such as car problems, rain, long lines) before ultimately entering the booth to cast a vote. This experiment took place several days before the 2008 November presidential election.

Some versions were written in first person ("I entered the voting booth) while some were written in third person ("Paul entered the voting booth"). In addition, some versions featured a student who attended the same university as the participants, while in other versions, the protagonist in the story attended a different university.

After reading the story, the participants completed a questionnaire that measured their level of experience-taking - how much they adopted the perspective of the character in the story. For example, they were asked to rate how much they agreed with statements like "I found myself feeling what the character in the story was feeling" and "I felt I could get inside the character's head."

The results showed that participants who read a story told in first-person, about a student at their own university, had the highest level of experience-taking. And a full 65 percent of these participants reported they voted on Election Day, when they were asked later.

In comparison, only 29 percent of the participants voted if they read the first-person story about a student from a different university.

"When you share a group membership with a character from a story told in first-person voice, you're much more likely to feel like you're experiencing his or her life events," Libby said. "And when you undergo this experience-taking, it can affect your behavior for days afterwards."

While people are more likely to lose themselves in a character who is similar to themselves, what happens if they don't learn that a character is not similar until later in a story?

In one experiment, 70 male, heterosexual college students read a story about a day in the life of another student. There were three versions - one in which the character was revealed to be gay early in the story, one in which the student was identified as gay late in the story, and one in which the character was heterosexual.

Results showed that the students who read the story where the character was identified as gay late in the narrative reported higher levels of experience-taking than did those who read the story where the character's homosexuality was announced early.

"If participants knew early on that the character was not like them - that he was gay - that prevented them from really experience-taking," Libby said.

"But if they learned late about the character's homosexuality, they were just as likely to lose themselves in the character as were the people who read about a heterosexual student."

Even more importantly, the version of the story participants read affected how they thought about gays.

Those who read the gay-late narrative reported significantly more favorable attitudes toward homosexuals after reading the story than did readers of both the gay-early narrative and the heterosexual narrative.

Those who read the gay-late narrative also relied less on stereotypes of homosexuals - they rated the gay character as less feminine and less emotional than did the readers of the gay-early story.

"If people identified with the character before they knew he was gay, if they went through experience-taking, they had more positive views - the readers accepted that this character was like them," Kaufman said.

Similar results were found in a story where white students read about a black student, who was identified as black early or late in the story.

Libby said experience-taking is different from perspective-taking, where people try to understand what another person is going though in a particular situation - but without losing sight of their own identity.

"Experience-taking is much more immersive - you've replaced yourself with the other," she said.

The key is that experience-taking is spontaneous - you don't have to direct people to do it, but it happens naturally under the right circumstance.

"Experience-taking can be very powerful because people don't even realize it is happening to them. It is an unconscious process," Libby said.

Author: Jeff Grabmeier | Source: Ohio State University [May 07, 2012]

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Are You a Facebook Addict?

Are you a social media enthusiast or simply a Facebook addict? Researchers from Norway have developed a new instrument to measure Facebook addiction, the Bergen Facebook Addiction Scale.

More and more people get addicted to social media, such as Facebook. Researchers at University of Bergen have created a scale to measure Facebook addiction [Credit: Colourbox]

"The use of Facebook has increased rapidly. We are dealing with a subdivision of Internet addiction connected to social media," Doctor of Psychology Cecilie Schou Andreassen says about the study, which is the first of its kind worldwide.

Andreassen heads the research project “Facebook Addiction” at the University of Bergen (UiB). An article about the results has just been published in the renowned journal Psychological Reports. She has clear views as to why some people develop Facebook dependency.

"It occurs more regularly among younger than older users. We have also found that people who are anxious and socially insecure use Facebook more than those with lower scores on those traits, probably because those who are anxious find it easier to communicate via social media than face-to-face," Andreassen says.

People who are organised and more ambitious tend to be less at risk from Facebook addiction. They will often use social media as an integral part of work and networking.

"Our research also indicates that women are more at risk of developing Facebook addiction, probably due to the social nature of Facebook," Andreassen says.

According to Andreassen, the research also shows that Facebook addiction was related to extraversion. People with high scores on the new scale further tend to have a somewhat delayed sleep-wake rhythm.

Six warning signs

As Facebook has become as ubiquitous as television in our everyday lives, it is becoming increasingly difficult for many people to know if they are addicted to social media. Andreassen’s study shows that the symptoms of Facebook addiction resemble those of drug addiction, alcohol addiction, and chemical substance addiction.

The Bergen Facebook Addiction Scale is based on six basic criteria, where all items are scored on the following scale: (1) Very rarely, (2) Rarely, (3) Sometimes, (4) Often, and (5) Very often:
 

• You spend a lot of time thinking about Facebook or plan use of Facebook.

• You feel an urge to use Facebook more and more.

• You use Facebook in order to forget about personal problems.

• You have tried to cut down on the use of Facebook without success.

• You become restless or troubled if you are prohibited from using Facebook.

• You use Facebook so much that it has had a negative impact on your job/studies.

Andreassen’s study shows that scoring “often” or “always” on at least four of the seven items may suggest that you are addicted to Facebook.

About the Scale

In January 2011, 423 students – 227 women and 196 men – participated in tests for the Bergen Facebook Addiction Scale. The scale can facilitate treatment research, clinical assessment and can be used for the estimation of Facebook addiction prevalence in the general population worldwide.

The Bergen Facebook Addiction Scale has been developed at the Faculty of Psychology, University of Bergen in collaboration with the Bergen Clinics Foundation, Norway. The researchers involved are also working with instruments measuring other addictions, such as the recently introduced Bergen Work Addiction Scale.

Author: Sverre Ole Dronen | Source: University of Bergen [May 07, 2012]

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The gifts we keep on giving

Birthdays, graduations, Christmas, baby showers, bridal showers, bar and bat mitzvahs, Mother's Day, Father's Day, first marriages (and second.. and third…), wedding anniversaries, the spontaneous friendship gesture, the occasional sorry-about-that gesture, hostess gifts and presents that don't even fall into a recognizable category. The year is filled with opportunities and obligations to give and receive.

So who can blame someone for doing a little recycling, or as it is commonly known, regifting? Not the person who actually gave the original gift, despite what a regifter may think.

In an article to be published in a forthcoming issue of Psychological Science, a journal of the Association for Psychological Science, researchers from Stanford Graduate School of Business, the Harvard Business School and the London Business School explore the whole question of regifting from the perspective of both the original giver and the receiver who may or may not rewrap and regift.

In five studies they investigate whether the practice of "regifting", which is a social taboo, really is as offensive to givers as regifters assume. Over and over again, participants who had received gifts and were told to contemplate regifting thought that the original givers would be more offended than givers reported feeling.

"Regifitng isn't bad," said Gabrielle Adams from the London Business School. "In fact it is one way to ensure that gifts are passed along to those who will truly enjoy them. People shouldn't be afraid to pass along a gift they received to someone else."

In one study, 178 participants were divided into the roles of givers and receivers. They all read a scenario in which they were asked to imagine that they had recently been given a watch as a graduation gift. Givers were asked to imagine that the receiver had either regfited the watch to a friend or had thrown the watch in the trash. Receivers were asked to imagine that they had either regifted or trashed the watch.

The reactions to each scenario were measured on a five point "offensiveness" scale, which ranged from "very slightly or not at all" to extremely offended. Those who contemplated regifting the watch or pitching it, were asked to rate how offended the giver would be with either scenario. Givers did the same.

Givers were less offended when they learned that the receiver had regifted the watch than when they learned the receiver threw the gift away. But those who received the gift believed that givers would be equally offended no matter what option they took. They basically equated regifting with discarding.

"The finding that receivers think that regifting is as bad as throwing a gift in the trash was particularly interesting to us, " said Adams. "Givers thought throwing a gift away would be much worse than regifting it."

It all boils down to beliefs about entitlement, researchers say. Receivers feel that givers should have a say in what happens to their gifts, while givers feel that receivers are entitled to do whatever they like with a gift.

How to get everyone on the same page? Just add another holiday to the gift giving list; this one could be called National Regifting Day. Adams explains, "It turns out that National Regifting Day is one way to make receivers think regifting is less offensive."

Source: Association for Psychological Science [May 07, 2012]

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Regular jogging shows dramatic increase in life expectancy

Undertaking regular jogging increases the life expectancy of men by 6.2 years and women by 5.6 years, reveals the latest data from the Copenhagen City Heart study presented at the EuroPRevent2012 meeting. Reviewing the evidence of whether jogging is healthy or hazardous, Peter Schnohr told delegates that the study's most recent analysis (unpublished) shows that between one and two-and-a-half hours of jogging per week at a "slow or average" pace delivers optimum benefits for longevity. The EuroPRevent2012 meeting, held 3 May to 5 May 2012, in Dublin, Ireland, was organised by the European Association for Cardiovascular Prevention and Rehabilitation (EACPR), a registered branch of the European Society of Cardiology (ESC).

"The results of our research allow us to definitively answer the question of whether jogging is good for your health," said Schnohr, who is chief cardiologist of the Copenhagen City Heart Study, speaking in the "Assessing prognosis: a glimpse of the future" symposium on Saturday. "We can say with certainty that regular jogging increases longevity. The good news is that you don't actually need to do that much to reap the benefits."

The debate over jogging first kicked off in the 1970s when middle aged men took an interest in the past-time. "After a few men died while out on a run, various newspapers suggested that jogging might be too strenuous for ordinary middle aged people," recalled Schnohr.

The Copenhagen City Heart study, which started 1976, is a prospective cardiovascular population study of around 20,000 men and women aged between 20 to 93 years. The study, which made use of the Copenhagen Population Register, set out to increase knowledge about prevention of cardiovascular disease and stroke. Since then the study, which has resulted in publication of over 750 papers, has expanded to include other diseases such as heart failure, pulmonary diseases, allergy, epilepsy, dementia, sleep-apnea and genetics. The investigators have explored the associations for longevity with different forms of exercise and other factors.

For the jogging sub study, the mortality of 1,116 male joggers and 762 female joggers was compared to the non joggers in the main study population. All participants were asked to answer questions about the amount of time they spent jogging each week, and to rate their own perceptions of pace (defined as slow, average, and fast). "With participants having such a wide age span we felt that a subjective scale of intensity was the most appropriate approach," explained Schnohr, who is based at Bispebjerg University Hospital, Copenhagen.

The first data was collected between 1976 to 1978, the second from 1981 to 1983, the third from 1991 to 1994, and the fourth from 2001 to 2003. For the analysis participants from all the different data collections were followed using a unique personal identification number in the Danish Central Person Register. "These numbers have been key to the success of the study since they've allowed us to trace participants wherever they go," said Schnohr.

Results show that in the follow-up period involving a maximum of 35 years, 10,158 deaths were registered among the non-joggers and 122 deaths among the joggers. Analysis showed that risk of death was reduced by 44% for male joggers (age-adjusted hazard ratio 0.56) and 44% for female joggers (age-adjusted hazard ratio 0.56). Furthermore the data showed jogging produced an age adjusted survival benefit of 6.2 years in men and 5.6 years in women.

Further analysis exploring the amounts of exercise undertaken by joggers in the study has revealed a U-shaped curve for the relationship between the time spent exercising and mortality. The investigators found that between one hour and two and a half hours a week, undertaken over two to three sessions, delivered the optimum benefits, especially when performed at a slow or average pace. "The relationship appears much like alcohol intakes. Mortality is lower in people reporting moderate jogging, than in non-joggers or those undertaking extreme levels of exercise," said Schnohr.

The ideal pace can be achieved by striving to feel a little breathless. "You should aim to feel a little breathless, but not very breathless," he advised.

Jogging, said Schnohr, delivers multiple health benefits. It improves oxygen uptake, increases insulin sensitivity, improves lipid profiles (raising HDL and lowering triglycerides), lowers blood pressure, reduces platelet aggregation, increases fibrinolytic activity, improves cardiac function, bone density, immune function, reduces inflammation markers, prevents obesity, and improves psychological function. "The improved psychological wellbeing may be down to fact that people have more social interactions when they're out jogging," said Schnohr.

Source: European Society of Cardiology [May 03, 2012]

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Biophysics: Order in chaos

The process of skeletal muscle contraction is based around protein filaments sliding inside sarcomeres — the structural units of muscle fiber. Inside each sarcomere is a set of filament motors, which appear in different densities in different areas. Scientists previously thought that the motor force would change according to the filament load in the muscle, but recent studies have shown that the motor force actually maintains a constant level during the muscle contraction. Despite such breakthroughs, however, it remains unclear exactly how this constant force is maintained in an otherwise chaotic system.

Bin Chen of the A*STAR Institute of High Performance Computing and Huajian Gao at Brown University, US, have now built a model to illustrate the process of skeletal muscle contraction and show how a constant force can be sustained by the protein motors.

The two key proteins in muscle contraction are actin and myosin. Myosin drives the system, forming a thick filament made up of numerous motors which ‘grab’ onto, bind to and slide past the thinner actin filaments during contraction. This ‘grabbing’ and sliding motion has been shown to be fairly chaotic in nature, with attachment and release happening at random. When the weight of an object exerts a load on the filaments — for example, when you try to lift something up — the muscles must contract, requiring the protein motors to generate a force opposite to the load.

Chen and Gao have created a new skeletal muscle fiber model to demonstrate how contraction forces work. “Our model is designed for the sarcomere,” Chen explains. “We consider the thin filament as an elastic rod under a filament force, which is driven by multiple stochastic myosin motors that convert the chemical energy of adenosine-5'-triphosphate (ATP) hydrolysis into stored elastic energy and then function like swinging arms.”

The results show that the unique way in which the myosin motors randomly attach and release from actin, coupled with the elastic properties of the motors, generate a consistent force across the whole sarcomere. When there is a higher filament load, more myosin motors are attached to the actin, but the overall motor force remains constant.

“This regulation mechanism may exist in various biological processes and dramatically induces order within a chaotic system,” explains Chen. “Our modeling framework can also be further adapted to study the behaviors of other actomyosin complex structures, which is part of our plan for future work in this area.”

Author: Lee Swee Heng | Source: ResearchSEA [May 03, 2012]

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The bright side of death: Awareness of mortality can result in positive behaviors

Contemplating death doesn't necessarily lead to morose despondency, fear, aggression or other negative behaviors, as previous research has suggested. Following a review of dozens of studies, University of Missouri researchers found that thoughts of mortality can lead to decreased militaristic attitudes, better health decisions, increased altruism and helpfulness, and reduced divorce rates.

"According to terror management theory, people deal with their awareness of mortality by upholding cultural beliefs and seeking to become part of something larger and more enduring than themselves, such as nations or religions," said Jamie Arndt, study co-author and professor of psychological sciences. "Depending on how that manifests itself, positive outcomes can be the result."

For example, in one study American test subjects were reminded of death or a control topic and then either imagined a local catastrophe or were reminded of the global threat of climate change. Their militaristic attitudes toward Iran were then evaluated. After being reminded of death, people who were reminded of climate change were more likely to express lower levels of militarism than those who imagined a local disaster.

"The differences seen in this study resulted from the size of the group with which the test subjects identified," said Ken Vail, lead author and psychology doctoral student. "In both cases, they responded to the awareness of mortality by seeking to protect the relevant groups. When the threat was localized, subjects aggressively defended their local group; but when the threat was globalized, subjects associated themselves with humanity as a whole and became more peaceful and cooperative."

After real catastrophes, such as the terrorist attacks of 9/11 and the Oklahoma City bombing, people's heightened fear and awareness of death had both positive and negative effects.

"Both the news media and researchers tended to focus on the negative reaction to these acts of terrorism, such as violence and discrimination against Muslims, but studies also found that people expressed higher degrees of gratitude, hope, kindness and leadership after 9/11." Vail said. "In another example, after the Oklahoma City bombing, divorce rates went down in surrounding counties. After some stimuli escalates one's awareness of death, the positive reaction is to try to reaffirm that the world has positive aspects as well."

In their personal lives, people also were influenced to make positive choices after their awareness of death was increased. Studies found that conscious thoughts of death can inspire intentions to exercise more. Other studies found that keeping mortality in mind can reduce smoking and increase sunscreen use.

Even subconscious awareness of death can more influenced behavior. In one experiment, passers-by who had recently overheard conversations mentioning the value of helping were more likely to help strangers if they were walking within sight of cemeteries.

"Once we started developing this study we were surprised how much research showed positive outcomes from awareness of mortality," said Arndt. "It seems that people may be just as capable of doing the opposite and 'looking on the bright side of death,' as the Monty Python song says."

Source: University of Missouri-Columbia [April 30, 2012]

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Highly Religious People Are Less Motivated by Compassion Than Are Non-Believers

"Love thy neighbor" is preached from many a pulpit. But new research from the University of California, Berkeley, suggests that the highly religious are less motivated by compassion when helping a stranger than are atheists, agnostics and less religious people.

In three experiments, social scientists found that compassion consistently drove less religious people to be more generous. For highly religious people, however, compassion was largely unrelated to how generous they were, according to the findings which are published in the most recent online issue of the journal Social Psychological and Personality Science.

The results challenge a widespread assumption that acts of generosity and charity are largely driven by feelings of empathy and compassion, researchers said. In the study, the link between compassion and generosity was found to be stronger for those who identified as being non-religious or less religious.

"Overall, we find that for less religious people, the strength of their emotional connection to another person is critical to whether they will help that person or not," said UC Berkeley social psychologist Robb Willer, a co-author of the study. "The more religious, on the other hand, may ground their generosity less in emotion, and more in other factors such as doctrine, a communal identity, or reputational concerns."

Compassion is defined in the study as an emotion felt when people see the suffering of others which then motivates them to help, often at a personal risk or cost.

While the study examined the link between religion, compassion and generosity, it did not directly examine the reasons for why highly religious people are less compelled by compassion to help others. However, researchers hypothesize that deeply religious people may be more strongly guided by a sense of moral obligation than their more non-religious counterparts.

"We hypothesized that religion would change how compassion impacts generous behavior," said study lead author Laura Saslow, who conducted the research as a doctoral student at UC Berkeley.

Saslow, who is now a postdoctoral scholar at UC San Francisco, said she was inspired to examine this question after an altruistic, nonreligious friend lamented that he had only donated to earthquake recovery efforts in Haiti after watching an emotionally stirring video of a woman being saved from the rubble, not because of a logical understanding that help was needed.

"I was interested to find that this experience -- an atheist being strongly influenced by his emotions to show generosity to strangers -- was replicated in three large, systematic studies," Saslow said.

In the first experiment, researchers analyzed data from a 2004 national survey of more than 1,300 American adults. Those who agreed with such statements as "When I see someone being taken advantage of, I feel kind of protective towards them" were also more inclined to show generosity in random acts of kindness, such as loaning out belongings and offering a seat on a crowded bus or train, researchers found.

When they looked into how much compassion motivated participants to be charitable in such ways as giving money or food to a homeless person, non-believers and those who rated low in religiosity came out ahead: "These findings indicate that although compassion is associated with pro-sociality among both less religious and more religious individuals, this relationship is particularly robust for less religious individuals," the study found.

In the second experiment, 101 American adults watched one of two brief videos, a neutral video or a heartrending one, which showed portraits of children afflicted by poverty. Next, they were each given 10 "lab dollars" and directed to give any amount of that money to a stranger. The least religious participants appeared to be motivated by the emotionally charged video to give more of their money to a stranger.

"The compassion-inducing video had a big effect on their generosity," Willer said. "But it did not significantly change the generosity of more religious participants."

In the final experiment, more than 200 college students were asked to report how compassionate they felt at that moment. They then played "economic trust games" in which they were given money to share -- or not -- with a stranger. In one round, they were told that another person playing the game had given a portion of their money to them, and that they were free to reward them by giving back some of the money, which had since doubled in amount.

Those who scored low on the religiosity scale, and high on momentary compassion, were more inclined to share their winnings with strangers than other participants in the study.

"Overall, this research suggests that although less religious people tend to be less trusted in the U.S., when feeling compassionate, they may actually be more inclined to help their fellow citizens than more religious people," Willer said.

In addition to Saslow and Willer, other co-authors of the study are UC Berkeley psychologists Dacher Keltner, Matthew Feinberg and Paul Piff; Katharine Clark at the University of Colorado, Boulder; and Sarina Saturn at Oregon State University.

The study was funded by grants from UC Berkeley's Greater Good Science Center, UC Berkeley's Center for the Economics and Demography of Aging, and the Metanexus Institute.

Author: Yasmin Anwar | Source: University of California - Berkeley [April 30, 2012]

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